--- title: Pressure Decay Test Method - Multi-Q description: The Pressure Decay Test Method enables you to test container closure systems including vials and ampoules that contain toxic product or oil based liquids --- [SEPHA](https://sepha.com/) [Contact](https://sepha.com/contact/) - Our Solutions - [Products](https://sepha.com/products) - [Leak Testing Solutions](https://sepha.com/products/leak-testing/) - [Packaging Solutions](https://sepha.com/products/packaging-solutions/) - [Deblistering Solutions](https://sepha.com/products/deblistering/) - [Container Types](https://sepha.com/container-types) - [Blister Packs](https://sepha.com/container-type/blister-packs/) - [Bottles](https://sepha.com/container-type/bottles/) - [IV Bags](https://sepha.com/container-type/iv-bags/) - [Vials](https://sepha.com/container-type/vials/) - [Ampoules](https://sepha.com/container-type/ampoules/) - [Pre-filled Syringes](https://sepha.com/container-type/pre-filled-syringes/) - [Flexible Packaging](https://sepha.com/container-type/flexible-packaging/) - [Medical Device Packaging](https://sepha.com/container-type/medical-device-packaging/) - [Test Methods](https://sepha.com/test-methods) - [Vacuum Decay](https://sepha.com/test-methods/vacuum-decay/) - [Pressure Decay](https://sepha.com/test-methods/pressure-decay/) - [Force Decay](https://sepha.com/test-methods/force-decay/) - [Vacuum Deflection](https://sepha.com/test-methods/vacuum-deflection/) - [3D Volumetric Measurement](https://sepha.com/test-methods/vacuum-deflection/#volumetric-measurement) - Standards & Regulations - [ASTM F2338-09](https://sepha.com/standards/astm-f2338-09/) - [ASTM F3169-16](https://sepha.com/standards/astm-f3169-16/) - [USP 1207](https://sepha.com/regulations/usp1207/) - [21 CFR Part 11](https://sepha.com/regulations/21-cfr-part-11/) - [Services](https://sepha.com/services/) - [Contract Packaging](https://sepha.com/services/contract-packaging/) - [Insights & Resources](https://sepha.com/insights-and-resources/) - [Resources](https://sepha.com/resources) - [Blog & News](https://sepha.com/blog-news/) - [Events](https://sepha.com/events) - [FAQs](https://sepha.com/faq/) - [Contact](https://sepha.com/contact/) - [Support](https://sepha.com/support/) - [info@sepha.com](mailto:info@sepha.com) - [+44 (0)28 9048 4848](tel:+44(0)2890484848) - [Our Organisation](https://sepha.com/our-organisation/) # Pressure Decay Test Method - Multi-Q ![Vials for pressure decay testing](https://lp.sepha.com/hs-fs/hubfs/Vials%20for%20pressure%20decay%20testing.jpg?width=1400&height=1000&name=Vials%20for%20pressure%20decay%20testing.jpg) The [Sepha Multi-Q Pressure Decay Method](https://sepha.com/products/leak-testing/multi-q/multi-q-pressure-decay/)method enables manufacturers to test the integrity of container closure systems of pharmaceutical containers including vials, ampoules, bottles and other containers that contain toxic product, oil based liquids or lyo/powder. CC systems need to protect sterile products from potential contamination to ensure product safety throughout its shelf life. ![Sepha Multi-Q Pressure Decay](https://lp.sepha.com/hs-fs/hubfs/Sepha%20Multi-Q%20Pressure%20Decay.jpg?width=269&height=202&name=Sepha%20Multi-Q%20Pressure%20Decay.jpg)The Multi-Q can identify leaks and channel leaks as low as 5µm (dependent on container type and content). The method is deterministic and non-destructive and can be used for stability testing, clinical trials and in process quality control testing. Pressure decay testing is referenced in the revised [USP 1207](https://blog.sepha.com/usp-1207-opening-the-ccit-toolbox?hsLang=en) guidance as one of the recommended deterministic test [CCIT](https://blog.sepha.com/container-closure-integrity-testing-ccit-safety-in-numbers?hsLang=en) methods that are preferred over probabilistic procedures such as the bubble test or blue bath method. The revised chapter will be applied to vials, ampoules, syringes, and bags. In addition, the machine includes software developed for manufacturers that need to comply with FDA 21 CFR Part 11. The software enables safe interaction between the machine, data reports and audit trails and protects reports from being edited or deleted.   ## Multi-Q Pressure Decay Video   ## Multi-Q Brochure Download Download the [Sepha Multi-Q](https://sepha.com/products/leak-testing/multi-q/) brochure by completing the form on the right to find out more about the versatile Container Closure Integrity Test system and learn how you can help improve your package assurance process. If you would like to discuss your CCIT requirements in more detail, please get in touch on +44(0)2890 48 48 48, +1 616-888-9081(USA) or via the button below.   [![Get in Touch](https://no-cache.hubspot.com/cta/default/6244888/6550110e-2723-4fdd-bb47-dcda7cb6aa3b.png)](https://cta-redirect.hubspot.com/cta/redirect/6244888/6550110e-2723-4fdd-bb47-dcda7cb6aa3b)   Interesting links - [Multi-Q Pressure Decay product page](https://sepha.com/products/leak-testing/multi-q/multi-q-pressure-decay/) - [Multi-Q Vacuum Decay product page](https://sepha.com/products/leak-testing/multi-q/multi-q-vacuum-decay/) - [Blog post 'Container Closure Integrity Testing (CCIT): safety in numbers](https://blog.sepha.com/container-closure-integrity-testing-ccit-safety-in-numbers?hsLang=en) ### Download Brochure ### Sign up for our Sepha newsletter Sign Up [SEPHA](https://sepha.com/) [Twitter](https://twitter.com/sephaltd?lang=en) [Linkedin](https://www.linkedin.com/company/sepha-ltd) Founded in 1980 SEPHA has established a global reputation for innovation and development of specialised, high quality equipment for use in the manufacture of pharmaceutical blister packs, medical device and healthcare products. Our products enable customers to create high quality blister packs, to accurately detect leaks and weak seals in packaging, and to recover high value products from blister packs. ### Products - [Leak Testing](https://sepha.com/products/leak-testing/) - [Multi-Q](https://sepha.com/products/leak-testing/multi-q/) - [PakScan](https://sepha.com/products/leak-testing/pakscan/) - [VisionScan 3D](https://sepha.com/products/leak-testing/visionscan-3d/) - [Deblistering](https://sepha.com/products/deblistering/) - [PressOut Manual Wide](https://sepha.com/products/deblistering/pressout-manual-wide/) - [PressOut Semi-Automatic](https://sepha.com/contact/pressout-semi-automatic/) - [PressOut Universal](https://sepha.com/products/deblistering/pressout-universal/) - [PressOut Universal Mini](https://sepha.com/products/deblistering/pressout-universal-mini/) - [Clic-Open Ampoule Opener](https://sepha.com/products/deblistering/clic-open/) - [Packaging](https://sepha.com/products/packaging-solutions/) - [EZ Blister](https://sepha.com/products/packaging-solutions/ez-blister/) - [EZ Blister+](https://sepha.com/products/packaging-solutions/ez-blister-plus/) - [EZ Blister MAP](https://sepha.com/products/packaging-solutions/ez-blister-map/) - [EZ MedPak](https://sepha.com/products/packaging-solutions/ez-medpak/) ### Connectivity - [MESConnect](https://sepha.com/connectivity/mes-connect/) ### Container Types - [Blister Packs](https://sepha.com/container-type/blister-packs/) - [Bottles](https://sepha.com/container-type/bottles/) - [IV Bags](https://sepha.com/container-type/iv-bags/) - [Vials](https://sepha.com/container-type/vials/) - [Ampoules](https://sepha.com/container-type/ampoules/) - [Pre-filled Syringes](https://sepha.com/container-type/pre-filled-syringes/) - [Flexible Packaging](https://sepha.com/container-type/flexible-packaging/) - [Medical Device Packaging](https://sepha.com/container-type/medical-device-packaging/) ### Standards & Regulations - [ASTM F2338-24](https://sepha.com/standards/astm-f2338-24/) - [ASTM F3169-16](https://sepha.com/standards/astm-f3169-16/) - [USP 1207](https://sepha.com/regulations/usp1207/) - [21 CFR Part 11](https://sepha.com/regulations/21-cfr-part-11/) ### Test Methods - [CCIT](https://sepha.com/test-methods/container-closure-integrity-testing/) - [Vacuum Decay](https://sepha.com/test-methods/vacuum-decay/) - [Pressure Decay](https://sepha.com/test-methods/pressure-decay/) - [Force Decay](https://sepha.com/test-methods/force-decay/) - [Vacuum Deflection](https://sepha.com/test-methods/vacuum-deflection/) - [3D Volumetric Measurement](https://sepha.com/test-methods/vacuum-deflection/#volumetric-measurement) ### Services - [Our Services](https://sepha.com/services/) ### Insights & Resources - [Customer Stories](https://sepha.com/customer-stories/) - [Resources](https://sepha.com/resources/) - [Blog & News](https://sepha.com/blog-news/) - [Events](https://sepha.com/events/) - [FAQS](https://sepha.com/faq/) ### Links - [Our Organisation](https://sepha.com/our-organisation/) - [Meet our team](https://sepha.com/our-organisation/meet-our-team/) - [Contact](https://sepha.com/contact/) - [Privacy Policy](https://sepha.com/privacy-policy/) - [Cookie Policy](https://sepha.com/cookie-policy/) - [Tax Strategy](https://www.tasigroup.com/uk-tax-strategy-statement/) Copyright © 2024 Sepha. All rights reserved. Wurkhouse [Site by WURKHOUSE](https://wurkhouse.com)